My research is on genetics, genomics and breeding of marine molluscs. I am interested in genetic and genomic research that advance our understanding of molluscan biology and evolution, as well as studies that may lead to the development of superior stocks for molluscan aquaculture. Specific research in my lab may include selective breeding for disease resistance and superior growth, the development of triploids and tetraploids for aquaculture, classification and phylogenetics of molluscs, identification and mapping of genetic variations underlie economically important traits such as disease resistance, genome/transcriptome sequencing and characterization, molluscan immunity and stress adaptation, and the evolution of sex determination.
Dr. Ximing Guo received his Ph.D. from University of Washington (Seattle). He joined the Haskin Shellfish Research Laboratory in 1992 as a postdoctoral researcher and became a Research Assistant Professor in 1995. He was promoted to Associate Professor in 2001 and has been a Full Professor since 2007.
Guo, X., Y. He, L. Zhang, C. Lelong and A. Jouaux. 2015. Immune and stress responses in oysters with insights on adaptation. Fish & Shellfish Immunology, 46:107-119. http://dx.doi.org/10.1016/j.fsi.2015.05.018
Zhang, G., X. Fang, X. Guo, L. Li, R. Luo, F. Xu, et al (80). 2012. The oyster genome reveals stress adaptation and complexity of shell formation. Nature, 490:49-54. (http://dx.doi.org/10.1038/nature11413)
He, Y., H. Yu, Z. Bao, Q. Zhang and X. Guo. 2012. Mutation in promoter region of a serine protease inhibitor confers Perkinsus marinus resistance in the eastern oyster (Crassostrea virginica). Fish & Shellfish Immunology 33: 411-417.
Guo, X., Y. Wang, Z. Xu and H. Yang. 2009. Chromosome set manipulation in shellfish. Pp 165 – 195 in: New Technologies in Aquaculture: Improving Production Efficiency, Quality and Environmental management, G. Burnell and G. Allan (eds). Woodhead Publishing.
Wang, H. and X. Guo. 2008. Identification of Crassostrea ariakensis and related oysters by multiplex species-specific PCR. J. Shellfish Res., 27(3):481-487.
Guo, X., Y. Wang, L. Wang and J-H Lee. 2008. Oysters. Pp 161 – 175 in: Genome Mapping and Genomics in Fishes and Aquatic Animals, Thomas D. Kocher & Chittaranjan Kole (Eds), Springer, Berlin.
Tanguy, A., X. Guo and S.E. Ford. 2004. Discovery of genes expressed in response to Perkinsus marinus challenge in eastern (Crassostrea virginica) and Pacific (C. gigas) oysters. Gene, 338:121-131.
Yu, Z. and X. Guo. 2003. Genetic linkage map of the eastern oyster Crassostrea virginica Gmelin. Biol. Bull. 204: 327–338.
Guo, X., D. Hedgecock, W.K. Hershberger, K. Cooper and S.K. Allen, Jr. 1998. Genetic determinants of protandric sex in Crassostrea oyster. Evolution, 52(2):394-402.
Guo, X., G. DeBrosse and S.K. Allen, Jr. 1996. All-triploid Pacific oysters (Crassostrea gigas Thunberg) produced by mating tetraploids and diploids. Aquaculture, 142:149-161.